The threat of avian influenza A (H5N1). Part I: epidemiologic concerns and virulence determinants
Identifieur interne : 001419 ( Main/Exploration ); précédent : 001418; suivant : 001420The threat of avian influenza A (H5N1). Part I: epidemiologic concerns and virulence determinants
Auteurs : Jindrich Cinatl Jr [Allemagne] ; Martin Michaelis [Allemagne] ; Hans W. Doerr [Allemagne]Source :
- Medical Microbiology and Immunology [ 0300-8584 ] ; 2007-12-01.
Abstract
Abstract: Among emerging and re-emerging infectious diseases, influenza constitutes one of the major threats to mankind. In this review series epidemiologic, virologic and pathologic concerns raised by infections of humans with avian influenza virus A/H5N1 are discussed. This first part concentrates on epidemiologic concerns and virulence determinants. H5N1 spread over the world and caused a series of fowl pest outbreaks. Significant human-to-human transmissions have not been observed yet. Mutations that make the virus more compatible with human-to-human transmission may occur at any time. Nevertheless, no one can currently predict with certainty whether H5N1 will become a human pandemic virus.
Url:
- https://api.istex.fr/ark:/67375/VQC-TLK7GCZH-7/fulltext.pdf
- https://api.istex.fr/ark:/67375/VQC-N26CZ5CC-J/fulltext.pdf
DOI: 10.1007/s00430-007-0042-5
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Abstract: Among emerging and re-emerging infectious diseases, influenza constitutes one of the major threats to mankind. In this review series epidemiologic, virologic and pathologic concerns raised by infections of humans with avian influenza virus A/H5N1 are discussed. This first part concentrates on epidemiologic concerns and virulence determinants. H5N1 spread over the world and caused a series of fowl pest outbreaks. Significant human-to-human transmissions have not been observed yet. Mutations that make the virus more compatible with human-to-human transmission may occur at any time. Nevertheless, no one can currently predict with certainty whether H5N1 will become a human pandemic virus.</div>
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